every time. 1200 fps or so. 90 gr quikshok 380, loaded to 1900 fps in a 38 Casull should work pretty well. The bullet breaking into 3, fairly large frags (slug is segmented lenthwise) and those frages tumbling, really adds to the tissue damage andshck effect. Made of solid copper, 60grs at 2200 fps, 9x25 Dillon, that would be pretty effective,indeed.