The March 2004 Guns & Ammo just came today. In the article "Classic Test" by Steve Comus, they feature the Colt Python. In one paragragh it reads:
"Although the standard chambering for the Python was the .357 magnum, some were made in .38 special, .41 magnum, .44 special and even the .257 winchester magnum. Only prototypes of Pythons chambered for .22 LR and .22 WMR were made."