If the person doesn't want to start with a .22, an most don't (maybe its not macho, I don't know), I recommend a Stainless .357 with adjustable sights. Ammo is cheap, light loads for newbies are available, the gun holds its value if they get bored with it, the stainless finish is more forgiving when the firearm is neglected, its "gunkid" proof, no levers and switches to confuse them and if they practice its a fairly dependable defence gun when used with speedloaders. I like the S&W M66 or the GP-100 myself.